During ToeJam and Earl's return trip home, a figure of Earthlings hitchhiked on their starship and are now overrunning major planet Funkotron. ToeJam and Earl must chase down the Earthlings in order to enamour them in big jars and ship them back to Earth in spaceships. It is also their funky mission to find 10 darling physical objects belonging to Lamont the "Funkapotamus," the beginning of all funk in the universe, so they can carry him to return to his loved funk-filled planet. ToeJam and Earl must use their "funk powers," like the Funk Move and Funk Scan, to help in dodging and catching the Earthlings.